USE OF DEXMEDETOMIDINE IN GENERAL AND THORACIC SURGERY: HEMODYNAMIC CONTROL AND POST-ANESTHETIC OUTCOMES

Autores

  • Pedro Henrique Lima Domingues
  • Rodolfo de Oliveira Medeiros
  • Cristiano Machado Galhardi
  • Leonardo de Marco Silva
  • Beatriz Schmoeller Rode
  • Murilo Gonçalves Faria
  • Daniel Tsumotu Suzuki
  • Thifany Pereira Nunes Kotai
  • Eduardo Gomes Pato Nogueira
  • José Antonio Pizzolato Neto
  • Laysa Ohana Mada
  • Augusto Fonseca Rego
  • Kaliana Moura Silva
  • Gabriela Maria Paes de Oliveira
  • Felipe Ravazzi Guzzo

DOI:

https://doi.org/10.36557/2009-3578.2025v11n2p5947-5960

Palavras-chave:

Dexmedetomidine; Anesthesia; Thoracic Surgery; Hemodynamic Stability; Post-Anesthetic Recovery.

Resumo

Dexmedetomidine, a highly selective α2-adrenergic receptor agonist, has become one of the most relevant pharmacological agents in modern anesthesiology due to its ability to promote cooperative sedation, effective analgesia, and hemodynamic stability. Its sympatholytic and anxiolytic profile allows precise modulation of the autonomic response to surgical stress, making it particularly useful in general and thoracic surgical procedures, in which the preservation of cardiovascular and respiratory function is essential for anesthetic success. This narrative review aimed to critically analyze the use of dexmedetomidine in these contexts, highlighting its effects on intraoperative hemodynamic control and post-anesthetic outcomes reported in contemporary literature. The reviewed evidence indicates that the drug contributes to reduced heart rate, blood pressure stability, lower opioid consumption, and shorter extubation time, in addition to providing better emergence quality, lower incidence of delirium, and prolonged analgesia.Such benefits directly influence the patient’s functional recovery and help prevent cardiorespiratory complications. However, the literature still lacks standardization regarding optimal doses, infusion time, and pharmacological combinations, reinforcing the need for individualized protocols. It is concluded that dexmedetomidine represents a valuable adjuvant in multimodal anesthesia, capable of integrating safety, stability, and patient well-being across different surgical settings.

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Publicado

2025-10-27

Como Citar

Domingues, P. H. L., Medeiros, R. de O., Galhardi, C. M., Silva, L. de M., Rode, B. S., Faria, M. G., … Guzzo, F. R. (2025). USE OF DEXMEDETOMIDINE IN GENERAL AND THORACIC SURGERY: HEMODYNAMIC CONTROL AND POST-ANESTHETIC OUTCOMES. INTERFERENCE: A JOURNAL OF AUDIO CULTURE, 11(2), 5947–5960. https://doi.org/10.36557/2009-3578.2025v11n2p5947-5960

Edição

v. 11 n. 2 (2025): IJAC - QUALIS A2

Seção

Revisão de Literatura

Licença

Copyright (c) 2025 Pedro Henrique Lima Domingues, Rodolfo de Oliveira Medeiros, Cristiano Machado Galhardi, Leonardo de Marco Silva, Beatriz Schmoeller Rode, Murilo Gonçalves Faria, Daniel Tsumotu Suzuki, Thifany Pereira Nunes Kotai, Eduardo Gomes Pato Nogueira, José Antonio Pizzolato Neto, Laysa Ohana Mada, Augusto Fonseca Rego, Kaliana Moura Silva, Gabriela Maria Paes de Oliveira, Felipe Ravazzi Guzzo

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